Design Rationale
The Benefit of PEEK is a modulus of elasticity matching cancellous bone and radiolucency allowing physicians to accurately assess fusion progression over time.
Engineered, Fully Interconnected Porous Structure throughout the implant, enabled by proprietary Fused Filament Fabrication 3D Printer, mimics natural bone.
Proprietary HAFUSE (Hydroxyapatite) Surface Nano-Texturing designed to promote faster and enhanced Osseointegration.*
Evonik VESTAKEEP® i4 3DF high-performance medical implant-grade PEEK filament.
Material Comparison
The flexibility of Inspire lattice architecture is crafted in compliance with Wolff’s Law to reduce the
overall stiffness and prevent stress shielding by matching the modulus of elasticity of cancellous bone.
Structure Drives Biology
Implant Construct
MAG 1X
Macro-Structure
MAG 40X
Micro-Roughness
MAG 100X
Nano-Texture
MAG 40,000X
- Proprietary Fused Filament Fabrication (FFF) – novel porous scaffolding structure mimics natural human bone
- 100% fully Interconnected Porosity
- Pore size distribution between 100 – 600 microns promoting Osteoconduction
- Diamond shape pores (Triply Periodic Minimal Surface, TPMS), documented in literature as possessing superior biomechanic and biologic properties*
- Micron-scale surface roughness presents hydrophilic surfaces promoting bone apposition and enhanced Osseointegration*
- HAFUSE surface nano texturing mimics physiologic bone
Osseointegration – Mimics the Physiology of Cancellous Bone
Inspire Implant
Human Cancellous Bone
HAFUSE Promotes Osseointegration and Osteogenesis
- HA is bonded to 100% of the implant surface throughout the entire structure
- Nano textured surface enables bone to anchor directly to the implant surface, creating superior mechanical stability
- Osteogenic potential provided by internal cavities driven by diamond structure, surface roughness, and HAFUSE drives Immunomodulation
- Physiologic bone-like structures promote Osteogenesis and Immunomodulation leading to regenerative bone formation encouraging faster and enhanced Osseointegration between the implant and bone tissue.*
SEM of HAFUSE Nano-Texturing at 40,000x magnification
12 week Micro CT Images (ovine)*
12 week Histology Images (ovine)*
A Breakthrough in Additive Manufacturing
The Inspire HAFUSE interbody platform is manufactured with a proprietary, patented 3D printer utilizing novel equipment, electronics, software, firmware, and slicing algorithms developed by the company. This advancement positions Curiteva to control product development of 3D printed PEEK devices from inception to commercialization.
First 3D FFF printer to consistently create novel PEEK implant structures
Continuous and contiguous filament deposition
Fabrication layers incorporate engineered (TPMS) Diamond Structures
Final implant structure provides superior biomechanics and enhanced biological Osseointegration
A TRUE PLATFORM TECHNOLOGY
The Inspire Porous PEEK HAFUSE platform represents a revolution in biomaterials by delivering an interconnected porous, engineered structure ideal for Osseointegration, radiographic assessment, and optimal patient outcomes.
Spine Applications
Orthopedic Applications
Sports Medicine Applications
*Reference available upon request.
System Features
Key Features
Key Features
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Key Features